| 21:30 PM ETNationwide Arena | ||
 | Washington Capitals 0-0-0, 0pts | |
 | Columbus Blue Jackets 0-0-0, 0pts | |
| Projected Goalies | ||
 | Joel Hofer - WSH 0 W - 0 L - 0 OTL - nan GAA - nan SV% | |
 | Andrei Vasilevskiy - CBJ 0 W - 0 L - 0 OTL - nan GAA - nan SV% | |
| Players to watch | ||
 | Michael McCarron - WSH 0 G - 0 A - 0 PTS | |
 | Jack Eichel - CBJ 0 G - 0 A - 0 PTS | |
| PREVIEW: Blue Jackets opens season against Capitals | ||
| 20:30 PM ETPNC Center | ||
 | Pittsburgh Penguins 0-0-0, 0pts | |
 | Carolina Hurricanes 0-0-0, 0pts | |
| Projected Goalies | ||
 | Linus Ullmark - PIT 0 W - 0 L - 0 OTL - nan GAA - nan SV% | |
 | Jordan Binnington - CAR 0 W - 0 L - 0 OTL - nan GAA - nan SV% | |
| Players to watch | ||
 | J.T. Miller - PIT 0 G - 0 A - 0 PTS | |
 | Ryan O'Reilly - CAR 0 G - 0 A - 0 PTS | |
| PREVIEW: Hurricanes opens season against Penguins | ||
| 22:00 PM ETTD Garden | ||
 | Buffalo Sabres 0-0-0, 0pts | |
 | Boston Bruins 0-0-0, 0pts | |
| Projected Goalies | ||
 | Juuse Saros - BUF 0 W - 0 L - 0 OTL - nan GAA - nan SV% | |
 | Spencer Knight - BOS 0 W - 0 L - 0 OTL - nan GAA - nan SV% | |
| Players to watch | ||
 | Nathan MacKinnon - BUF 0 G - 0 A - 0 PTS | |
 | Nick Suzuki - BOS 0 G - 0 A - 0 PTS | |
| PREVIEW: Bruins opens season against Sabres | ||
| 19:30 PM ETScotiabank Arena | ||
 | Montreal Canadiens 0-0-0, 0pts | |
 | Toronto Maple Leafs 0-0-0, 0pts | |
| Projected Goalies | ||
 | Mackenzie Blackwood - MTL 0 W - 0 L - 0 OTL - nan GAA - nan SV% | |
 | Brandon Bussi - TOR 0 W - 0 L - 0 OTL - nan GAA - nan SV% | |
| Players to watch | ||
 | Robert Thomas - MTL 0 G - 0 A - 0 PTS | |
 | Leon Draisaitl - TOR 0 G - 0 A - 0 PTS | |
| PREVIEW: Maple Leafs opens season against Canadiens | ||
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